ϟ

Everything research has to say on giardiasis in 2023

Here's a list of the most cited journal articles on giardiasis, an infection caused by the parasite Giardia lamblia

Giardiasis is an infection caused by the parasite Giardia lamblia. It is most commonly contracted through the consumption of contaminated water or food, or through close contact with an infected person. Symptoms of giardiasis include diarrhea, abdominal cramps, bloating, and flatulence. In some cases, the infection may cause no symptoms at all.

Research has shown that giardiasis is a significant public health problem worldwide. It is one of the most common causes of waterborne and foodborne illnesses, and it is estimated to affect millions of people each year, particularly in developing countries.

The main treatment for giardiasis is the use of antiparasitic drugs such as metronidazole and tinidazole. Studies have shown that these drugs are effective in most cases, but in some cases, the infection may persist or recur after treatment.

Prevention of giardiasis mainly focused on avoiding contaminated water or food, proper hand hygiene, and treatment of infected individuals. Research has also looked into the development of a giardia vaccine. So far, no vaccine is available for the general population but some experimental vaccines are being tested.

In addition, research has investigated the genetic diversity and population structure of Giardia, epidemiology and risk factors for giardiasis, and the development of diagnostic tests that are more accurate and less invasive than traditional methods.

DOI: 10.1371/journal.pntd.0010402
2022
Cited 4 times
COX-2 is required to mediate crosstalk of ROS-dependent activation of MAPK/NF-κB signaling with pro-inflammatory response and defense-related NO enhancement during challenge of macrophage-like cell line with Giardia duodenalis
Yudan Zhao, Yongwu Yang, Min Liu, Xuening Qin, Xiran Yu, Huimin Zhao, Xiaoyun Li, Wei Li
Giardia
Inflammation
MAPK/ERK pathway
DOI: 10.1080/09593330.2020.1811396
2022
Cited 4 times
Wastewater treatment performance in microbiological removal and (oo)cyst viability assessed comparatively to fluorescence decay
Raphael Corrêa Medeiros, Kamila Jessie Sammarro Silva, Luiz Antonio Daniel
Wastewater
Sewage treatment
Giardia
DOI: 10.1016/j.tmaid.2022.102287
2022
Cited 3 times
Screening for parasites in migrant children
Jorge A. Bustamante, Talía Sainz, Fátima Ara Montojo, Mariana Díaz Almirón, Subirats M, Dolores González Vega, María José Mellado, M. García López-Hortelano
Eosinophilia
Medicine
Strongyloidiasis
DOI: 10.3389/fimmu.2022.817468
2022
Cited 3 times
Mucosal Defense Against Giardia at the Intestinal Epithelial Cell Interface
Shahram Solaymani-Mohammadi
Giardia lamblia
Immunology
Giardia
DOI: 10.1093/jtm/taab120
2022
Cited 3 times
Treatment strategies for nitroimidazole-refractory giardiasis: a systematic review
Daniel L. Bourque, Andreas Neumayr, Michael Libman, Li Chen
Nitroimidazole
Medicine
Nitazoxanide
DOI: 10.1371/journal.pone.0264812
2022
Assessment of prevalence of Giardia lamblia infection and its associated factors among government elementary school children from Sidama zone, SNNPR, Ethiopia
Sunil Tulshiram Hajare, Yeinewub Chekol, Nitin M. Chauhan
Giardia lamblia
Hygiene
Environmental health
DOI: 10.1093/nar/gkac046
2022
Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite <i>Giardia lamblia</i>
Disha-Gajanan Hiregange, Andre Rivalta, Tanaya Bose, Elinor Breiner-Goldstein, Sarit Samiya, G. Cimicata, Liudmila Kulakova, Ella Zimmerman, Anat Bashan, Osnat Herzberg, Ada Yonath
Giardia lamblia
Biology
Ribosome
DOI: 10.2147/idr.s346705
2022
Helicobacter pylori Pathogenicity Islands and Giardia lamblia Cysteine Proteases in Role of Coinfection and Pathogenesis
Mihret Tilahun, Alemu Gedefie, Chernet Belayhun, Zenawork Sahle, Admasu Abera
Giardia lamblia
Helicobacter pylori
Coinfection
DOI: 10.3390/microorganisms10050940
2022
Genotypic and Epidemiologic Profiles of Giardia duodenalis in Four Brazilian Biogeographic Regions
Deiviane Aparecida Calegar, Beatriz C. Nunes, Kerla J. L. Monteiro, Polyanna A. A. Bacelar, Brenda B. C. Evangelista, Mayron Morais Almeida, Jurecir Silva, Jéssica P. Santos, Márcio N. Boia, Lauren Hubert Jaeger, Filipe Anibal Carvalho-Costa
Amazon rainforest
Giardia
Genetic diversity
DOI: 10.1093/infdis/jiab287
2022
Quinacrine Treatment of Nitroimidazole-Refractory Giardiasis
Karin A. Ydsten, Urban Hellgren, Hilmir Asgeirsson
Nitroimidazole
Tolerability
Metronidazole
DOI: 10.1590/0074-02760210280
2022
Giardiasis in urban and rural Amazonas, Brazil is driven by zoonotic and cosmopolitan A and B assemblages
Lisiane Lappe dos Reis, Túllio Romão Ribeiro da Silva, Francisco Carlos de Oliveira Braga, Naara Macedo do Nascimento, Katia Costa de Menezes, Alessandra Nava, Natália A. de Souza Lima, Ana Carolina Paulo Vicente
Giardia
Amazon rainforest
Biology
DOI: 10.1186/s13568-022-01484-w
2022
Role of anti-Giardia recombinant cyst wall protein IgG polyclonal antibodies in diagnosis and protection
Ahmed Maher, Donia Atallah, Mahmoud Hassan, Mariam Hammad, Mohaned Galal, Saif-Eldin Mohamed, Yara Abdelkafy, Alyaa Farid
Giardia
Polyclonal antibodies
Antibody
DOI: 10.1128/iai.00672-21
2022
The Anti-Apoptotic Role of COX-2 during In Vitro Infection of Human Intestinal Cell Line by Giardia duodenalis and The Potential Regulators
Yongwu Yang, Yudan Zhao, Lin Liu, Weining Zhu, Shuo Jia, Xiaoyun Li, Wei Li
Biology
Apoptosis
Poly ADP ribose polymerase
DOI: 10.1107/s2053230x21013595
2022
Crystal structure of a hypothetical protein from Giardia lamblia
Dylan Bodhi Beard, Seonna Bristol, Kayla Cosby, Amber R. Davis, Courtney Manning, Lionel Perry, Lauren Snapp, Arian Toy, Kayla Wheeler, Jeremy R. Young, Bart L. Staker, Tracy L. Arakaki, Jan Abendroth, Sandhya Subrahamanian, Thomas E. Edwards, Peter J. Myler, Oluwatoyin A. Asojo
Giardia lamblia
Giardia
Structural genomics
DOI: 10.3389/fcimb.2022.974200
2022
Giardial lipid rafts share virulence factors with secreted vesicles and participate in parasitic infection in mice
Brian Grajeda, Atasi De Chatterjee, Carmen M. Villalobos, Breanna Pence, Cameron T. Ellis, Vanessa A. Enriquez, Sourav Roy, Sukla Roychowdhury, Aaron K. Neumann, Igor C. Almeida, Steven E. Patterson, Siddhartha Das
Biology
Virulence
Giardia
DOI: 10.1080/09593330.2020.1866083
2022
Detection and removal of Giardia spp. cysts and Cryptosporidium spp. oocysts by anaerobic reactors in Brazil
Fernanda P. Valdez, Luan de Souza Leite, José Fernandes Filho, Mariana Daniel Tango, Luiz Antonio Daniel
Giardia
Cryptosporidium
Wastewater
DOI: 10.1186/s13071-022-05269-9
2022
Giardia duodenalis in patients with diarrhea and various animals in northeastern China: prevalence and multilocus genetic characterization
Yanchen Wu, Lan Yao, Hongshuang Chen, Weizhe Zhang, Yanyan Jiang, Fengkun Yang, Aiqin Liu, Yujuan Shen
Biology
Parasitology
Giardia
DOI: 10.1089/fpd.2021.0073
2022
Prevalence of <i>Giardia duodenalis</i> Among Dogs in China from 2001 to 2021: A Systematic Review and Meta-Analysis
Ziyu Zhao, Ming-Han Li, Chuang Lyu, Xiangzhu Meng, Yifeng Qin, Xinbo Yang, Ning Ma, Quan Zhao, Yuqing Zhang, Jing Jiang
Giardia
Veterinary medicine
Meta-analysis
DOI: 10.1645/21-26
2022
Giardia duodenalis Genotyping Not Linked to Clinical Symptomatology and Nutritional Status of School-Aged Children of Soledad and Galapa Municipality Schools, Atlántico, Colombia
Karen Muñoz Salas, Alma Polo Barrios, Carolina Gonzalez, Juan Rodríguez Macias, Carmiña L Vargas Zapata
Genotype
Giardia
Feces
DOI: 10.1111/pim.12908
2022
Evaluation of immune response and haematological parameters in infected male albino rats by giardiasis
Mabrouk A. Abo-Zaid, Aishah Ali Hamdi
Mean corpuscular volume
Biology
Immune system
DOI: 10.1016/j.molbiopara.2022.111504
2022
Inorganic phosphate transporter in Giardia duodenalis and its possible role in ATP synthesis
Ayra Diandra Carvalho-de-Araújo, Luiz Fernando Carvalho-Kelly, Claudia F. Dick, José Roberto Meyer-Fernandes
Biology
Pi
Symporter
DOI: 10.3390/su142114572
2022
Principal Component Analysis (PCA)–Geographic Information System (GIS) Modeling for Groundwater and Associated Health Risks in Abbottabad, Pakistan
Tahir Ali Akbar, Azka Javed, Siddique Ullah, Waheed Ullah, Arshid Pervez, Raza Ali Akbar, Muhammad Faisal Javed, Abdullah Mohamed, Abdeliazim Mustafa Mohamed
Geographic information system
Principal component analysis
Inverse distance weighting
DOI: 10.3390/microorganisms10020273
2022
Genome Sequence and Assessment of Safety and Potential Probiotic Traits of Lactobacillus johnsonii CNCM I-4884
Anne-Sophie Boucard, Isabelle Florent, Bruno Polack, Philippe Langella, Luis G. Bermúdez-Humarán
Biology
Probiotic
Lactobacillus gasseri
DOI: 10.1111/imcb.12550
2022
<i>Giardia lamblia</i> regulates the production of proinflammatory cytokines through activating the NOD2‐Rip2‐ROS signaling pathway in mouse macrophages
Xu Zhang, Xin Li, Yanhui Yu, Xichen Zhang, Xiaocen Wang, Nan Zhang, Mengge Chen, Pengtao Gong, Jianhua Li
Proinflammatory cytokine
NOD1
Giardia lamblia
DOI: 10.1515/sjpain-2021-0122
2022
Prevalence of fibromyalgia 10 years after infection with <i>Giardia lamblia</i>: a controlled prospective cohort study
Gunnhild S Hunskar, Guri Rortveit, Sverre Litleskare, Geir Egil Eide, Kurt Hanevik, Nina Langeland, Knut-Arne Wensaas
Fibromyalgia
Medicine
Irritable bowel syndrome