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The most cited papers on viral infections in 2022

Here's a list of the 25 most cited journal articles in 2022 about viral infections

Virus-related illnesses are referred to as viral infections (a small germ that uses your cells to reproduce). Colds, the flu, COVID-19, stomach flu, warts, and herpes are examples of common viral infections. While many viruses disappear on their own, some can lead to serious or long-lasting diseases. In this post, you will find the most cited journal articles on viral infections in 2022.

DOI: 10.1056/nejmoa2116044

Cited 602 times

Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients

Angélica Jayk Bernal, Monica M Gomes da Silva, Dany B Musungaie, Evgeniy Kovalchuk, Antonio Gonzalez, Virginia Delos Reyes, Alejandro Martín-Quirós, Yoseph Caraco, Angela Williams-Diaz, Michelle L Brown, Jiejun Du, Alison Pedley, Christopher Assaid, Julie Strizki, Jay A Grobler, Hala H Shamsuddin, Robert Tipping, Hong Wan, Amanda Paschke, Joan R Butterton, Matthew G Johnson, Carisa De Anda, null

Interim analysis

DOI: 10.1016/s1473-3099(22)00228-6

Cited 382 times

Clinical features and management of human monkeypox: a retrospective observational study in the UK

Hugh Adler, Susan Gould, Paul Hine, Luke B Snell, Waison Wong, Catherine F Houlihan, Jane C Osborne, Tommy Rampling, Mike BJ Beadsworth, Christopher JA Duncan, Jake Dunning, Tom E Fletcher, Ewan R Hunter, Michael Jacobs, Saye H Khoo, William Newsholme, David Porter, Robert J Porter, Libuše Ratcliffe, Matthias L Schmid, Malcolm G Semple, Anne J Tunbridge, Tom Wingfield, Nicholas M Price, Mike Abouyannis, Asma Al-Balushi, Stephen Aston, Robert Ball, Nicholas J Beeching, Thomas J Blanchard, Ffion Carlin, Geraint Davies, Angela Gillespie, Scott R Hicks, Marie-Claire Hoyle, Chinenye Ilozue, Luke Mair, Suzanne Marshall, Anne Neary, Emmanuel Nsutebu, Samantha Parker, Hannah Ryan, Lance Turtle, Chris Smith, Jon van Aartsen, Naomi F Walker, Stephen Woolley, Anu Chawla, Ian Hart, Anna Smielewska, Elizabeth Joekes, Cathryn Benson, Cheryl Brindley, Urmi Das, Chin K Eyton-Chong, Claire Gnanalingham, Clare Halfhide, Beatriz Larru, Sarah Mayell, Joanna McBride, Claire Oliver, Princy Paul, Andrew Riordan, Lekha Sridhar, Megan Storey, Audrey Abdul, Jennifer Abrahamsen, Breda Athan, Sanjay Bhagani, Colin S Brown, Oliver Carpenter, Ian Cropley, Kerrie Frost, Susan Hopkins, Jessica Joyce, Lucy Lamb, Adrian Lyons, Tabitha Mahungu, Stephen Mepham, Edina Mukwaira, Alison Rodger, Caroline Taylor, Simon Warren, Alan Williams, Debbie Levitt, Denise Allen, Jill Dixon, Adam Evans, Pauline McNicholas, Brendan Payne, D Ashley Price, Uli Schwab, Allison Sykes, Yusri Taha, Margaret Ward, Marieke Emonts, Stephen Owens, Alina Botgros, Sam T Douthwaite, Anna Goodman

Retrospective cohort study

DOI: 10.1016/s1473-3099(21)00648-4

Cited 349 times

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study

Anika Singanayagam, Seran Hakki, Jake Dunning, Kieran J Madon, Michael A. Crone, Aleksandra Koycheva, Nieves Derqui-Fernandez, Jack L Barnett, Michael G Whitfield, Robert Varro, Andre Charlett, Rhia Kundu, Joe Fenn, Jessica Cutajar, Valerie Quinn, Emily Conibear, Wendy S. Barclay, Paul S. Freemont, Graham P. Taylor, Shazaad Ahmad, Maria Zambon, Neil M. Ferguson, Ajit Lalvani, Anjna Badhan, Simon Dustan, Chitra Tejpal, Anjeli V Ketkar, J. S. Narean, Sarah Hammett, Eimear McDermott, Timesh D Pillay, Hamish Houston, Constanta Luca, Jada Samuel, Samuel Bremang, Samuel Evetts, John Poh, Charlotte Anderson, David C. Jackson, Shahjahan Miah, Joanna Ellis, Angie Lackenby

Contact tracing

DOI: 10.1038/s41586-022-04980-y

Cited 325 times

BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

Yunlong Richard Cao, Ayijiang Yisimayi, Fanchong Jian, Weiliang Song, Tianhe Xiao, Lei Wang, Shuo Du, Jing Wang, Qianqian Li, Xiaosu Chen, Yuanling Yu, Peng Wang, Zhiying Zhang, Pulan Liu, Ran An, Xiaohua Hao, Yao Wang, Jing Wang, Rui Feng, Haiyan Sun, Lijuan Zhao, Wen Zhang, Dong Zhao, Jiang Zheng, Lingling Yu, Can Li, Na Zhang, Rui Wang, Xiao Niu, Sijie Yang, Xuetao Song, Yangyang Chai, Ye Hu, Yansong Shi, Linlin Zheng, Zhiqiang Li, Qingqing Gu, Fei Shao, Weijin Huang, Jin ronghua, Zhongyang Shen, Youchun Wang, Xiangxi Wang, Junyu Xiao, Xiaoliang Sunney Xie

DOI: 10.1001/jama.2022.0470

Cited 304 times

Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants

Emma K. Accorsi, Amadea Britton, Katherine E. Fleming-Dutra, Zachary R. Smith, Nong Shang, Gordana Derado, Joseph D. Miller, Stephanie J. Schrag, Jennifer R. Verani

Coronavirus disease 2019 (COVID-19)

DOI: 10.1038/s41590-021-01122-w

Cited 266 times

The T cell immune response against SARS-CoV-2

DOI: 10.1038/s41586-022-04441-6

Cited 250 times

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

Peter J. Halfmann, Shun Iida, Kiyoko Iwatsuki-Horimoto, Tadashi Maemura, Maki Kiso, Suzanne M. Scheaffer, Tamarand L. Darling, Astha Joshi, Samantha Loeber, Gagandeep Singh, Stephanie L. Foster, Baoling Ying, James Brett Case, Zhenlu Chong, Bradley Whitener, Juan Moliva, Katharine Floyd, Michiko Ujie, Noriko Nakajima, Mutsumi Ito, Ryan Wright, Ryuta Uraki, Prajakta Warang, Matthew Gagne, Rong Li, Yuko Sakai-Tagawa, Yanan Liu, Deanna Larson, Jorge E. Osorio, Juan P. Hernández-Ortiz, Amy R. Henry, Karl Ciouderis, Kelsey R. Florek, Mit Patel, Abby Odle, Lok-Yin Roy Wong, Allen C. Bateman, Zhongde Wang, Venkata Viswanadh Edara, Zhenlu Chong, John Franks, Trushar Jeevan, Thomas P. Fabrizio, Jennifer DeBeauchamp, Lisa Kercher, Patrick Seiler, Ana S. Gonzalez-Reiche, Emilia Mia Sordillo, Lauren A. Chang, Harm van Bakel, Viviana Simon, B. Alburquerque, H. Alshammary, A. A. Amoako, S. Aslam, R. Banu, C. Cognigni, M. Espinoza-Moraga, K. Farrugia, A. van de Guchte, Z. Khalil, M. Laporte, I. Mena, A. E. Paniz-Mondolfi, J. Polanco, A. Rooker, L. A. Sominsky, Daniel C. Douek, Nancy J. Sullivan, Larissa B. Thackray, Hiroshi Ueki, Seiya Yamayoshi, Masaki Imai, Stanley Perlman, Richard J. Webby, Robert A. Seder, Mehul S. Suthar, Adolfo García-Sastre, Michael Schotsaert, Tadaki Suzuki, Adrianus C. M. Boon, Michael S. Diamond, Yoshihiro Kawaoka, null

Genetically modified mouse

DOI: 10.1038/s41591-021-01676-0

Cited 235 times

mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant

Henning Gruell, Kanika Vanshylla, Pinkus Tober-Lau, David Hillus, Philipp Schommers, Clara Lehmann, Florian Kurth, Leif E. Sander, Florian Klein

Neutralizing antibody

DOI: 10.1038/s41586-022-04460-3

Cited 227 times

T cell responses to SARS-CoV-2 spike cross-recognize Omicron

Roanne Keeton, Marius Belmondo Tincho, Amkele Ngomti, Richard Baguma, Ntombi Benede, Akiko Suzuki, Khadija Khan, Sandile Cele, Mallory Bernstein, Farina Karim, Sharon V Madzorera, Thandeka Moyo-Gwete, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Daniel Mutithu, Olukayode Aremu, Cari Stek, Elsa du Bruyn, Mieke A Van Der Mescht, Zelda de Beer, Talita R de Villiers, Annie Bodenstein, Gretha van den Berg, Adriano Mendes, Amy Strydom, Marietjie Venter, Jennifer Giandhari, Yeshnee Naidoo, Sureshnee Pillay, Houriiyah Tegally, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Robert J Wilkinson, Tulio de Oliveira, Linda-Gail Bekker, Glenda Gray, Veronica Ueckermann, Theresa Rossouw, Michael T. Boswell, Jinal N. Bhiman, Penny L. Moore, Alex Sigal, Ntobeko A B Ntusi, Wendy A Burgers, Catherine Riou

Coronavirus disease 2019 (COVID-19)

DOI: 10.1038/s41467-022-28089-y

Cited 201 times

Viral infection and transmission in a large, well-traced outbreak caused by the SARS-CoV-2 Delta variant

Baisheng Li, Aiping Deng, Kuibiao Li, Yao Hu, Zhencui Li, Yaling Shi, Qianling Xiong, Zhe Liu, Qianfang Guo, Lirong Zou, Huan Zhang, Meng Zhang, Fangzhu Ouyang, Juan Su, Wenzhe Su, Jing Xu, Huifang Lin, Jing Sun, Jinju Peng, Huiming Jiang, Pingping Zhou, Ting Hu, Min Luo, Yingtao Zhang, Huanying Zheng, Jianpeng Xiao, Tao Liu, Mingkai Tan, Rongfei Che, Hanri Zeng, Zhonghua Zheng, Yushi Huang, Jianxiang Yu, Lina Yi, Jie Wu, Jingdiao Chen, Haojie Zhong, Xiaoling Deng, Min Kang, Oliver G. Pybus, Matthew Hall, Katrina A. Lythgoe, Yan Li, Jun Yuan, Jianfeng He, Jing Lu

Transmission (telecommunications)

DOI: 10.1038/s41591-022-01700-x

Cited 186 times

Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant

Yu Gao, Curtis Cai, Alba Grifoni, T. Müller, Julia Niessl, Anna Olofsson, Marion Humbert, Lotta Hansson, Anders Österborg, Peter Bergman, Puran Chen, Annika Olsson, Johan K. Sandberg, Daniela Weiskopf, David Price, Hans-Gustaf Ljunggren, Annika C. Karlsson, Alessandro Sette, Soo Aleman, Marcus Buggert

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

DOI: 10.1016/s0140-6736(22)00163-5

Cited 166 times

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Obbina Abani, Ali Abbas, Fatima Abbas, Mustafa Abbas, Sadia Abbasi, Hakam Abbass, Alfie Abbott, Nabeel Abdallah, Ashraf Abdelaziz, Mohamed Abdelfattah, Bushra Abdelqader, Basir Abdul, Althaf Abdul Rasheed, Ajibode Abdulakeem, Rezan Abdul-Kadir, Abdullah Abdullah, Abdulfatahi Abdulmumeen, Rasheed Abdul-Raheem, Niyaz Abdulshukkoor, Kula Abdusamad, Yazeed Abed El Khaleq, Mai Abedalla, Abeer Ul-Amna, Katrina Abernethy, Adebanke Aboaba, Hani Abo-Leyah, Ahmed Abou-Haggar, Mahmoud Abouibrahim, Miriam Abraham, Tizzy Abraham, Abraheem Abraheem, Judith Abrams, Hyacinth-John Abu, Ahmed Abu-Arafeh, Syed M Abubacker, Akata Abung, Yaa Aceampong, Amaka Achara, Devikumar Acharya, Sarah Acheampong, Janet Acheson, Andres Acosta, Catherine Acton, Jacqueline Adabie-Ankrah, Fiona Adam, Matthew Adam, Huzaifa Adamali, Carol Adams, Charlotte Adams, Kate Adams, Richard Adams, Tim Adams, Krishma Adatia, Kirsty Adcock, Ade Adebiyi, Ken Adegoke, Vicki Adell, Sherna Adenwalla, Oluwasegun A Adesemoye, Emmanuel O Adewunmi, Joyce Adeyemi, Binay Adhikari, Rina Adhikary, Gabrielle Adkins, Adnan Adnan, John Aeron-Thomas, Debbie Affleck, Carmel Afnan, Muhammad Afridi, Zainab A Aftab, Meenakshi Agarwal, Rachel Agbeko, Chris Agbo, Sunil Aggarwal, Arameh Aghababaie, Shafana Ahamed Sadiq, Mohamed H Ahammed Nazeer, Mohammad Ahmad, Syed Ahmad, Asim Ahmed, Bilal Ahmed, Forizuddin Ahmed, Hamze Ahmed, Irshad Ahmed, Khaled Ahmed, Liban Ahmed, Mahin Ahmed, Maria C Ahmed, Muhammad S Ahmed, Naseer Ahmed, Nausheen Ahmed, Osama Ahmed, Rajia A Ahmed, Rizwan Ahmed, Saif Ahmed, Sammiya Ahmed, Syed Ahmed, Syed Haris Ahmed, Roa Ahmed Ali, Sana Ahmed

Randomized controlled trial

Internal medicine

DOI: 10.1038/s41586-022-05053-w

Cited 161 times

Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5

Qian Wang, Yicheng Guo, Sho Iketani, Manoj S. Nair, Zhiteng Li, Hiroshi Mohri, Maple Wang, Jian Yu, Anthony Bowen, Jennifer Y Chang, Jayesh G Shah, Nadia Nguyen, Zhiwei Chen, Kathrine Meyers, Michael T Yin, Magdalena E Sobieszczyk, Zizhang Sheng, Yaoxing Huang, Lihong Liu, David D. Ho

DOI: 10.1056/nejmoa2116597

Cited 161 times

Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants

David W Eyre, Donald Taylor, Mark Purver, David Chapman, Tom Fowler, Koen B. Pouwels, A. Sarah Walker, Tim E. A. Peto

Transmission (telecommunications)

DOI: 10.1016/j.antiviral.2022.105252

Cited 147 times

Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern

Laura Vangeel, Winston Chiu, Steven De Jonghe, Piet Maes, Bram Slechten, Joren Raymenants, Emmanuel André, Pieter Leyssen, Johan Neyts, Dirk Jochmans

DOI: 10.1016/s1473-3099(22)00411-x

Cited 122 times

Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in London, UK: an observational analysis

Nicolò Girometti, Ruth Byrne, Margherita Bracchi, Joseph Heskin, Alan McOwan, Victoria Tittle, Keerti Gedela, Christopher Scott, Sheel Patel, Jesal Gohil, Diarmuid Nugent, Tara Suchak, Molly Dickinson, Margaret Feeney, Borja Mora-Peris, Katrina Stegmann, Komal Plaha, Geraint Davies, Luke S P Moore, Nabeela Mughal, David Asboe, Marta Boffito, Rachael Jones, Gary Whitlock

DOI: 10.1056/nejmoa2117128

Cited 119 times

Effectiveness of Covid-19 Vaccines over a 9-Month Period in North Carolina

Dan-Yu Lin, Yu Gu, Bradford Wheeler, Hayley Young, Shannon Holloway, Shadia-Khan Sunny, Zack Moore, Donglin Zeng

Coronavirus disease 2019 (COVID-19)

DOI: 10.1016/s0140-6736(22)01436-2

Cited 110 times

Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study

Eloy José Tarín-Vicente, Andrea Alemany, Manuel Agud-Dios, Maria Ubals, Clara Suñer, Andrés Antón, Maider Arando, Jorge Arroyo-Andrés, Lorena Calderón-Lozano, Cristina Casañ, José Miguel Cabrera, Pep Coll, Vicente Descalzo, María Dolores Folgueira, Jorge N García-Pérez, Elena Gil-Cruz, Borja González-Rodríguez, Christian Gutiérrez-Collar, Águeda Hernández-Rodríguez, Paula López-Roa, María de los Ángeles Meléndez, Julia Montero-Menárguez, Irene Muñoz-Gallego, Sara Isabel Palencia-Pérez, Roger Paredes, Alfredo Pérez-Rivilla, María Piñana, Nuria Prat, Aída Ramirez, Ángel Rivero, Carmen Alejandra Rubio-Muñiz, Martí Vall, Kevin Stephen Acosta-Velásquez, An Wang, Cristina Galván-Casas, Michael Marks, Pablo L Ortiz-Romero, Oriol Mitjà

DOI: 10.1016/j.cell.2022.01.018

Cited 107 times

Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination

Katharina Röltgen, Sandra C.A. Nielsen, Oscar Silva, Sheren F. Younes, None Maxim Zaslavsky, Cristina Costales, Fan Yang, Oliver F. Wirz, Daniel Solis, Ramona A. Hoh, Aihui Wang, Prabhu S. Arunachalam, Deana Colburg, Shuchun Zhao, Emily Haraguchi, Alexandra S. Lee, Mihir M. Shah, Monali Manohar, Iris Chang, Fei Gao, Vamsee Mallajosyula, Chunfeng Li, James Liu, Massa J. Shoura, Sayantani B. Sindher, Ella Parsons, Naranjargal J. Dashdorj, Naranbaatar D. Dashdorj, Robert Monroe, Geidy E. Serrano, Thomas G. Beach, R. Sharon Chinthrajah, Gregory W. Charville, James L. Wilbur, Jacob N. Wohlstadter, Mark M. Davis, Bali Pulendran, Megan L. Troxell, George B. Sigal, Yasodha Natkunam, Benjamin A. Pinsky, Kari C. Nadeau, Scott D. Boyd

Germinal center

DOI: 10.1016/j.scitotenv.2021.150121

SARS-CoV-2 RNA concentrations in wastewater foreshadow dynamics and clinical presentation of new COVID-19 cases

Fuqing Wu, Amy Xiao, Jianbo Zhang, Katya Moniz, Noriko Endo, Federica Armas, Richard Bonneau, Megan A. Brown, Mary Bushman, Peter R. Chai, Claire Duvallet, Timothy B. Erickson, Katelyn Foppe, Newsha Ghaeli, Xiaoqiong Gu, William P. Hanage, Katherine H. Huang, Wei Lin Lee, Mariana Matus, Kyle A. McElroy, Jonathan Nagler, Steven F Rhode, Mauricio Santillana, Joshua A. Tucker, Stefan Wuertz, Shijie Zhao, Janelle R. Thompson, Eric J. Alm

DOI: 10.1016/s0140-6736(22)00838-8

Shanghai's life-saving efforts against the current omicron wave of the COVID-19 pandemic

Xinxin Zhang, Wenhong Zhang, Saijuan Chen

Coronavirus disease 2019 (COVID-19)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

DOI: 10.1038/s41591-022-01780-9

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

Ben Killingley, Alex Mann, Mariya Kalinova, Alison Boyers, Niluka Goonawardane, Jie Zhou, Kate Lindsell, Samanjit S. Hare, Jonathan Brown, Rebecca Frise, Emma Smith, Claire Hopkins, Nicolas Noulin, Brandon Löndt, Tom Wilkinson, Stephen Harden, Helen McShane, Mark Baillet, Anthony Gilbert, Michael Jacobs, Christine Charman, Priya Mande, Jonathan S. Nguyen-Van-Tam, Malcolm G Semple, Robert C. Read, Neil M. Ferguson, Peter J. M. Openshaw, W. Garth Rapeport, Wendy S. Barclay, Andrew P. Catchpole, Christopher Chiu

DOI: 10.1038/s41590-021-01091-0

Innate immunity: the first line of defense against SARS-CoV-2

Michael S. Diamond, Thirumala-Devi Kanneganti

Innate immune system

DOI: 10.3389/fcimb.2021.781429

SARS-COV-2 Variants: Differences and Potential of Immune Evasion

Sandro M. Hirabara, Tamires D. A. Serdan, Renata Gorjao, Laureane N. Masi, Tania C. Pithon-Curi, Dimas T. Covas, Rui Curi, Edison L. Durigon

DOI: 10.1002/jmv.27931

Epidemiological trends and clinical features of the ongoing monkeypox epidemic: A preliminary pooled data analysis and literature review

Nicola Luigi Bragazzi, Jude Dzevela Kong, Naim Mahroum, Christina Tsigalou, Rola Khamisy‐Farah, Manlio Converti, Jianhong Wu