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Top research published in 2022 about Lewy body disease (LBD)

Here's a list of the 25 most cited journal articles on Lewy body disease (LBD)

Dementia with Lewy bodies (DLB) also known as Lewy body disease (LBD) is a type of progressive dementia that affects movement, cognition, and behavior. It is characterized by abnormal aggregates of a protein called alpha-synuclein, called Lewy bodies, that accumulate in the brain. The symptoms of LBD are similar to those of Alzheimer's disease and Parkinson's disease and can include cognitive decline, confusion, memory loss, visual hallucinations, and problems with movement, balance, and coordination. It can also cause fluctuations in attention and alertness, and sudden onset of Parkinsonism such as stiffness, tremors, and difficulty with movement. LBD is the second most common type of progressive dementia after Alzheimer's disease.

DOI: 10.1136/jnnp-2021-327788

Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy

Leonidas Chouliaras, Alan J. Thomas, Maura Malpetti, Paul C. Donaghy, Joseph Kane, Elijah Mak, George Savulich, Maria A Prats-Sedano, Amanda Heslegrave, Henrik Zetterberg, Li Su, James B. Rowe, John T. O'Brien

Progressive supranuclear palsy

Dementia with Lewy bodies

Frontotemporal dementia

DOI: 10.1007/s00401-022-02408-5

Plasma biomarkers for Alzheimer’s Disease in relation to neuropathology and cognitive change

Denis S. Smirnov, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Joel Simrén, Juan Lantero-Rodriguez, Jonathan M. Schott, Annie Hiniker, Robert A. Rissman, David P. Salmon, Douglas Galasko

Hippocampal sclerosis

DOI: 10.1016/j.neuron.2022.03.004

ApoE Cascade Hypothesis in the pathogenesis of Alzheimer’s disease and related dementias

Yuka A Martens, Na Zhao, Chia-Chen Liu, Takahisa Kanekiyo, Austin J Yang, Alison M Goate, David M Holtzman, Guojun Bu

Apolipoprotein E

DOI: 10.1002/alz.12669

COVID‐19 breakthrough infections and hospitalizations among vaccinated patients with dementia in the United States between December 2020 and August 2021

Lindsey Wang, Pamela B Davis, David C Kaelber, Rong Xu

DOI: 10.1111/psyp.13934

Are there consistent abnormalities in event‐related EEG oscillations in patients with Alzheimer’s disease compared to other diseases belonging to dementia?

Bahar Güntekin, Tuba Aktürk, Xianghong Arakaki, Laura Bonanni, Claudio Del Percio, Rebecca M. Edelmayer, Francesca R Farina, Raffaele Ferri, Lutfu Hanoglu, Sanjeev Kumar, Roberta Lizio, Susanna Lopez, Brian R. Murphy, Giuseppe Noce, Fiona Randall, Alexander T. Sack, Fabrizio Stocchi, Görsev Yener, Ebru Yıldırım, Claudio Babiloni

DOI: 10.1002/acn3.51482

Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementia

Rebecca L. Miller, Zhude Tu, Jennifer Y. O’Shea, Kristin M. Andruska, Jialu Liu, Erin E. Franklin, Chandana Buddhala, Susan K. Loftin, John R. Cirrito, Richard J. Perrin, Nigel J. Cairns, Meghan C. Campbell, Joel S. Perlmutter, Robert H. Mach

DOI: 10.1007/s00401-022-02421-8

APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer’s disease with Lewy body pathology

Yunjung Jin, Fuyao Li, Berkiye Sonoustoun, Naveen Chandra Kondru, Yuka A. Martens, Wenhui Qiao, Michael G. Heckman, Tadafumi C. Ikezu, Zonghua Li, Jeremy D. Burgess, Danilyn Amerna, Justin O’Leary, Michael A. DeTure, Jing Zhao, Pamela J. McLean, Dennis W. Dickson, Owen A. Ross, Guojun Bu, Na Zhao

Apolipoprotein E

DOI: 10.1038/s41531-021-00273-9

Lewy body disease or diseases with Lewy bodies?

Katerina Mensikova, Radoslav Matěj, Carlo Colosimo, Raymond Rosales, Lucie Tučková, Jiří Ehrmann, Dominik Hraboš, Kristýna Kolařiková, Radek Vodicka, Radek Vrtěl, Martin Prochazka, Martin Nevrlý, Michaela Kaiserová, Sandra Kurčová, Pavel Otruba, Petr Kanovsky

Dementia with Lewy bodies

Synucleinopathies

DOI: 10.3390/molecules27113516

A Prospective Viewpoint on Neurological Diseases and Their Biomarkers

Mehrukh Zehravi, Janisa Kabir, Rokeya Akter, Sumira Malik, Ghulam Md Ashraf, Pooja Tagde, Sarker Ramproshad, Banani Mondal, Mohammad Ali Moni, Aurel George Mohan, Simona Cavalu

DOI: 10.1080/13607863.2022.2032601

Systematic review of pharmacological interventions for people with Lewy body dementia

Katrina E Watts, Nicholas J Storr, Phoebe G Barr, Anto P. Rajkumar

Dementia with Lewy bodies

DOI: 10.1523/jneurosci.1508-21.2022

S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia

Chang-Ki Oh, Nima Dolatabadi, Piotr Cieplak, Maria T Diaz-Meco, Jorge Moscat, John P Nolan, Tomohiro Nakamura, Stuart A Lipton

DOI: 10.1212/wnl.0000000000200878

α-Synuclein Seed Amplification Assays for Diagnosing Synucleinopathies

Giovanni Bellomo, Chiara De Luca, Federico Paolini Paoletti, Lorenzo Gaetani, Fabio Moda, Lucilla Parnetti

Synucleinopathies

Alpha-synuclein

Dementia with Lewy bodies

DOI: 10.1212/wnl.0000000000200110

Autopsy Validation of the Diagnostic Accuracy of <sup>123</sup>I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease

Tomoyasu Matsubara, Masashi Kameyama, Noriko Tanaka, Renpei Sengoku, Makoto Orita, Ko Furuta, Atsushi Iwata, Tomio Arai, Hirofumi Maruyama, Yuko Saito, Shigeo Murayama

DOI: 10.1001/jamapsychiatry.2021.4363

Associations Between Neuropsychiatric Symptoms and Neuropathological Diagnoses of Alzheimer Disease and Related Dementias

Davangere P. Devanand, Seonjoo Lee, Edward D. Huey, Terry E. Goldberg

Hippocampal sclerosis

DOI: 10.3390/metabo12020187

Human Brain Lipidomics: Pilot Analysis of the Basal Ganglia Sphingolipidome in Parkinson’s Disease and Lewy Body Disease

Aaron W Beger, Beatrix Dudzik, Randall L. Woltjer, Paul L. Wood

DOI: 10.4103/1673-5374.322463

Striatal oxidative damages and neuroinflammation correlate with progression and survival of Lewy body and Alzheimer diseases

Huifangjie Li, William C Knight, Jinbin Xu

Neuroinflammation

Neurodegeneration

DOI: 10.3389/fneur.2021.805135

Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium

Gregory Scott, Moriah R Arnold, Thomas G. Beach, Christopher H. Gibbons, Anumantha G. Kanthasamy, Russell M. Lebovitz, Afina W. Lemstra, Leslie M. Shaw, Charlotte E. Teunissen, Henrik Zetterberg, Angela E Taylor, Todd R. Graham, Bradley F. Boeve, Stephen N. Gomperts, Neill R. Graff-Radford, Charbel Moussa, Kathleen L. Poston, Liana S. Rosenthal, Marwan N. Sabbagh, Ryan Walsh, Miriam Weber, Melissa J. Armstrong, Jee Bang, Andrea Bozoki, Kimiko Domoto-Reilly, John E. Duda, Jori Fleisher, Douglas Galasko, James E. Galvin, Jennifer G. Goldman, Samantha K. Holden, Lawrence S. Honig, Daniel E. Huddleston, James B. Leverenz, Irene Litvan, Ishan C. Williams, Karen Marder, Alexander Pantelyat, Victoria S. Pelak, Douglas W. Scharre, Sharon J. Sha, Holly A. Shill, Zoltan Mari, Joseph F. Quinn, David J. Irwin

Dementia with Lewy bodies

DOI: 10.1002/alz.12765

Neuropathological correlates of neuropsychiatric symptoms in dementia

Lucy L. Gibson, Lea T. Grinberg, Dominic ffytche, Renata E. P. Leite, Roberta D. Rodriguez, Renata E. L. Ferretti‐Rebustini, Carlos A. Pasqualucci, Ricardo Nitrini, Wilson Jacob‐Filho, Dag Aarsland, Claudia K. Suemoto

DOI: 10.1007/s00415-022-10983-6

Visual hallucinations in Lewy body disease: pathophysiological insights from phenomenology

Fabrizia D'Antonio, Maddalena Boccia, Antonella Di Vita, Antonio Suppa, Andrea Fabbrini, Marco Canevelli, Francesca Caramia, Marco Fiorelli, Cecilia Guariglia, Stefano Ferracuti, Carlo de Lena, Dag Aarsland, Dominic Ffytche

Visual Hallucination

DOI: 10.1111/pcn.13485

Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment

Ito Kawakami, Jun-Ichi Iga, Sho Takahashi, Yi-Ting Lin, Hiroshige Fujishiro

Depression (economics)

DOI: 10.2147/cia.s360736

A Comparison of Cerebrospinal Fluid Beta-Amyloid and Tau in Idiopathic Normal Pressure Hydrocephalus and Neurodegenerative Dementias

Harun Muayad Said, Derya Kaya, Idil Yavuz, Fatma Sena Dost Günay, Zekiye Sultan Altun, Ahmet Turan Isik

Dementia with Lewy bodies

DOI: 10.1186/s13024-022-00560-w

LRP1 is a neuronal receptor for α-synuclein uptake and spread

Kai Chen, Yuka A. Martens, Axel Meneses, Daniel H. Ryu, Wenyan Lu, Ana Caroline Raulin, Fuyao Li, Jing Zhao, Yixing Chen, Yunjung Jin, Cynthia Linares, Marshall Goodwin, Yonghe Li, Chia-Chen Liu, Takahisa Kanekiyo, David M. Holtzman, Todd E. Golde, Guojun Bu, Na Zhao

Internalization

DOI: 10.1038/s41467-022-31787-2

α-Synuclein fibril-specific nanobody reduces prion-like α-synuclein spreading in mice

Yemima R. Butler, Yuqing Liu, Ramhari Kumbhar, Peiran Zhao, Kundlik Gadhave, Ning Wang, Yanmei Li, Xiaobo Mao, Wenjing Wang

DOI: 10.3233/jad-215587

Predictors of Mortality in Individuals with Dementia in the National Alzheimer’s Coordinating Center

Melissa J. Armstrong, Shangchen Song, Andrea M. Kurasz, Zhigang Li

Frontotemporal dementia

DOI: 10.1111/jsr.13589

Sleep apnea and the risk of dementia: A systematic review and meta‐analysis

Martin Guay-Gagnon, Sopharat Vat, Marie-France Forget, Maxime Tremblay-Gravel, Simon Ducharme, Quoc Dinh Nguyen, Philippe Desmarais

Vascular dementia